Hussey was diagnosed with breast cancer in 2008. She underwent a double mastectomy as a result. In 2017, her cancer returned, and Hussey had to undergo chemotherapy and radiation treatment to remove a tumor that was located between her heart and lungs, according to The Independent.

She also played Mary in the 1977 miniseries 'Jesus of Nazareth' and was memorable in 'Black Christmas' and 'Death on the Nile.'