Matthew Stafford passes for 281 yards and three touchdowns as the Rams bounce back from their loss to Carolina with a dominant win over the Arizona Cardinals.

Cardinals quarterback Jacoby Brissett passed for 271 yards, two touchdowns and an interception, and Michael Wilson had 11 catches for 142 yards and two scores, but that was about it on offense, as they rushed for only 51 yards as a team and had 314 total yards. The offense scored 17 points for the third consecutive game.

Rams vs. Cardinals will broadcast nationally on FOX in Week 14 of the 2025 NFL season. Kenny Albert and Jonathan Vilma will call the game from the booth at State Farm Stadium, Streaming options for the game include FuboTV, which offers a free trial to new subscribers.

The Los Angeles Rams gave the struggling Arizona Cardinals no reprieve in a dominating win at State Farm Stadium.

The Los Angeles Rams pulled quarterback Matthew Stafford from the Week 14 game against the Arizona Cardinals early. Here's why.

Quarterback Matthew Stafford's connection with wide receiver Puka Nacua and an efficient run game helped Los Angeles quickly put away Arizona (3-10). The victory gave the Rams their seventh season with at least 10 in nine years under head coach Sean McVay.

The Los Angeles Rams, led by quarterback Matthew Stafford, face the Arizona Cardinals, led by quarterback Jacoby Brissett, on Sunday, Dec. 7, 2025 at State Farm Stadium in Glendale, Ariz.

The Rams are 8.5-point favorites on the road, according to the latest Rams vs. Cardinals odds. The over/under for total points scored is 48.5. Check out the top NFL picks from the SportsLine Projection Model,