The Lions had an 11-game winning streak snapped in a 48-42 loss to the Bills but responded with a 34-17 rout at Chicago. The ...

Brock Purdy speaks with reporters on Fridayahead of San Francisco's Week 17 matchup against the Detroit Lions.Purdy explains ...

All the way back in January, Brock Purdy and the San Francisco 49ers secured their biggest win of the season, beating the ...

The Detroit Lions will know how meaningful their matchup with the San Francisco 49ers on Monday night will carry before they ...

Watch Greg Papa's full interview with Kyle Shanahan on "49ers Game Plan," airing at 11 p.m. PT Friday on NBC Sports Bay ...

The Detroit Lions' defense will line up for a favorable spot this Monday night against the San Francisco 49ers on the road. The Lions were rolling earlier this season, shutting down opposing offenses ...

Jameson Williams says he looks at 49ers' rematch "as just another game" ...

NFL Week 17 matchups, odds, picks and props following Christmas Day games. Three Saturday contests followed by Sunday's most ...

In the past 46 NFL seasons of a team having less that two wins with an experienced coach, just one coach was retained.

San Francisco 49ers QB Brock Purdy discussed supporting the new offensive line and the team's mindset heading into their ...

The Detroit Lions and San Francisco 49ers play Monday, Dec. 30, at the 49ers' Levi's Stadium in a game on the NFL Week 17 schedule. Which team will win the Monday Night Football game? Check out these ...

San Francisco 49ers defensive coordinator Nick Sorensen, offensive line/run game coordinator Chris Foerster, and quarterback ...