All lanes of the southbound 405 Freeway in Encino have reopened after an hours-long closure for a deadly crash.

A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks shut down traffic on all lanes early Tuesday.

A two-vehicle crash on the 405 Freeway killed a 72-year-old woman and a dog in West Los Angeles on Friday evening, officials ...

An 80-year-old woman and a 66-year-old man were critically injured, while a 60-year-old woman was hospitalized in fair ...

One person is dead and two others were injured following what investigators believe was a wrong-way crash involving three ...

LOS ANGELES - A woman and a dog were killed in a crash on the 405 Freeway on Friday night, and three other people were ...

A scantily-clad woman is in custody – but not before leading a police chase along the 405 Freeway in Los Angeles County. The ...

A 30-year-old man who died after driving north on the southbound side of the San Diego (405) Freeway in Sherman Oaks and slammed head-on into another vehicle was identified Wednesday by the Los ...

At least one person was killed in a reported wrong-way crash on the 405 Freeway in Encino that temporarily shut down of all southbound lanes Tuesday morning.

A woman and a dog were killed in a crash on the 405 in Westwood. Three other people were also injured, and another dog ...

An SUV was reportedly driving 60 to 70 mph northbound in the southbound carpool lanes of the 405 Freeway near Getty Center Drive just after 4 a.m. Tuesday, according to California Highway Patrol logs.